Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | ASAH1 | Q13510 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6926893 | 0.93 | TSHR (0.79) | TSHRALDH1A1ASAH1KDM4EKMT2A | |
| SCHEMBL205803 | 0.88 | TSHR (0.87) | TSHRALDH1A1ASAH1KDM4EKMT2A | |
| SCHEMBL28314136 | 0.87 | TSHR (0.58) | TSHRALDH1A1ASAH1KDM4EKMT2A | |
| SCHEMBL675169 | 0.82 | TSHR (0.79) | TSHRALDH1A1ASAH1KDM4EKMT2A | |
| SCHEMBL26619060 | 0.82 | TSHR (0.51) | TSHRALDH1A1ASAH1KDM4EKMT2A | |
| SCHEMBL203352 | 0.82 | TSHR (0.70) | TSHRALDH1A1ASAH1KDM4EKMT2A | |
| SCHEMBL7102687 | 0.81 | TSHR (0.83) | TSHRALDH1A1ASAH1KDM4EKMT2A | |
| SCHEMBL28386901 | 0.81 | ASAH1 (0.54) | TSHRALDH1A1ASAH1KMT2AMEN1 | |
| SCHEMBL203353 | 0.81 | TSHR (0.69) | TSHRALDH1A1ASAH1KDM4EKMT2A | |
| SCHEMBL202739 | 0.81 | ALDH1A1 (0.66) | TSHRALDH1A1ASAH1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866377-A1 | ORGANOSILOXANE COMPOSITIONS | Dow Corning Corporation (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006107762-A1 | ORGANOSILOXANE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2006-10-12 | — | — | WO | disclosed |