Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1205813 | 0.89 | MAPT (0.56) | SMN1; SMN2MAPTL3MBTL1TDP1RAB9A | |
| SCHEMBL6253299 | 0.84 | MAPT (0.51) | SMN1; SMN2MAPTL3MBTL1TDP1RAB9A | |
| SCHEMBL27670205 | 0.82 | MAPT (0.62) | SMN1; SMN2MAPTL3MBTL1TDP1RAB9A | |
| SCHEMBL18294040 | 0.81 | MAPT (0.49) | SMN1; SMN2MAPTL3MBTL1TDP1RAB9A | |
| SCHEMBL9492308 | 0.81 | KIF11 (0.53) | MAPTL3MBTL1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL9765294 | 0.80 | MAPT (0.54) | SMN1; SMN2MAPTL3MBTL1TDP1RAB9A | |
| SCHEMBL120180 | 0.80 | KMT2A (0.59) | SMN1; SMN2MAPTL3MBTL1TDP1RAB9A | |
| Butane SCHEMBL1043698 | 0.79 | KIF11 (0.47) | MAPTKMT2AMEN1HSD17B10ALDH1A1 | |
| SCHEMBL13290630 | 0.79 | MAPT (0.53) | SMN1; SMN2MAPTL3MBTL1TDP1RAB9A | |
| SCHEMBL11704915 | 0.79 | MAPT (0.53) | SMN1; SMN2MAPTL3MBTL1TDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110172019-A | The metal salt of malonic acid as the nucleating additive for crystalline thermoplastic | 印度石油有限公司 | 2019-08-27 | — | — | CN | disclosed |