SCHEMBL120180

SCHEMBL120180

CCC(=O)Oc1ccc(C(C)(C)C)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
ESR1 P03372 2/20 0.59
HIF1A Q16665 2/20 0.59
RECQL P46063 2/20 0.59
MAPT P10636 5/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
ELANE P08246 1/20 0.54
RAB9A P51151 3/20 0.50
HTT P42858 2/20 0.50
NPC1 O15118 1/20 0.50
NPSR1 Q6W5P4 2/20 0.49
MEN1 O00255 1/20 0.49
ALDH1A1 P00352 3/20 0.49
LMNA P02545 2/20 0.49
HSD17B10 Q99714 2/20 0.49
ALOX15 P16050 1/20 0.49
APEX1 P27695 1/20 0.49
MAPK1 P28482 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27670205 0.86 MAPT (0.62) KMT2ASMN1; SMN2RECQLMAPTL3MBTL1
SCHEMBL1205813 0.86 MAPT (0.56) KMT2ASMN1; SMN2RECQLMAPTL3MBTL1
SCHEMBL312147 0.85 KMT2A (0.76) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL23343706 0.85 BCL9 (0.57) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL1790593 0.85 KMT2A (0.56) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL9765294 0.85 MAPT (0.54) KMT2ASMN1; SMN2RECQLMAPTL3MBTL1
SCHEMBL28123833 0.84 KMT2A (0.54) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL22334762 0.84 KMT2A (0.54) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL11445596 0.83 KMT2A (0.73) KMT2ASMN1; SMN2ESR1HIF1ARECQL
SCHEMBL13290630 0.83 MAPT (0.53) KMT2ASMN1; SMN2RECQLMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 897 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210378920-A1 WET WIPER ARTICLES AND METHODS FOR CLEANING REMOVABLE DENTAL APPLIANCES Oral Health Technologies, LLC 2021-12-09 US claimed
US-20210038500-A1 DICLOFENAC AND HYALURONIC ACID COMBINATION TREATMENT FOR ORAL LEUKPOPLAKIA EHRENPREIS ELI D (US) 2021-02-11 US claimed
US-10857075-B2 Wet wiper articles and methods for cleaning removable dental appliances Oral Health Technologies, LLC (US) 2020-12-08 US claimed
WO-2020160344-A1 DICLOFENAC AND HYALURONIC ACID COMBINATION TREATMENT FOR ORAL LEUKPOPLAKIA EHRENPREIS ELI D (US) 2020-08-06 WO claimed
US-10702460-B2 Method of protecting teeth against erosion THE PROCTER & GAMBLE COMPANY (US) 2020-07-07 US claimed
US-20200179268-A1 DICLOFENAC AND HYALURONIC ACID COMBINATION TREATMENT FOR ORAL LEUKPOPLAKIA GI PHARMACEUTICALS, INC. AKS E2BIO CONSULTANTS 2020-06-11 US claimed
US-20200038298-A1 Method Of Protecting Teeth Against Erosion PROCTER & GAMBLE (US) 2020-02-06 US claimed
EP-2054494-B2 FLAVOR OILS WITH REDUCED SULFUR CONTENT AND USE IN ORAL CARE COMPOSITIONS PROCTER & GAMBLE (US) 2016-07-27 EP claimed
EP-2038012-B1 FLAVOR OILS WITH REDUCED SULFUR CONTENT AND USE IN ORAL CARE COMPOSITIONS PROCTER & GAMBLE (US) 2015-12-23 EP claimed
EP-2037866-B1 FLAVORS FOR ORAL COMPOSITIONS PROCTER & GAMBLE (US) 2015-11-11 EP claimed
WO-2008005549-A2 FLAVOR OILS WITH REDUCED SULFUR CONTENT AND USE IN ORAL CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2008-01-10 WO claimed
US-20080008665-A1 Flavors for oral compositions THE PROCTER & GAMBLE COMPANY 2008-01-10 US claimed
US-20060086048-A1 Foam dentifrice composition and method ROMLEY MICHAEL G 2006-04-27 US claimed
US-6042812-A CONSISTS OF PIPPERMINT OIL AND SPERMINT OIL, MENTHOL, ANETHOL, METHYL SALICYLATE, CINNAMON OIL, CLOVE OIL, OXANONE, DAIRY CREAM COMPONENT, FLUORIDE SOURCE AND AQUEOUS TOOTHPASTE, GEL OR LIQUID DENTRIFRICE OR MOUTH RINSE CARRIERS THE PROCTER & GAMBLE COMPANY (US) 2000-03-28 US claimed
EP-0941047-A1 FLAVOR SYSTEMS FOR ORAL CARE PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 1999-09-15 EP claimed
EP-0912260-A4 IMPROVED ANTI-GRAFFITI COATINGS AND METHOD OF GRAFFITI REMOVAL UNIV BRANDEIS (US) 1999-08-18 EP claimed
EP-0912260-A1 IMPROVED ANTI-GRAFFITI COATINGS AND METHOD OF GRAFFITI REMOVAL BRANDEIS UNIVERSITY (US) 1999-05-06 EP claimed
US-5773091-A WAX COATINGS BRANDEIS UNIVERSITY (US) 1998-06-30 US claimed
WO-1998023250-A1 FLAVOR SYSTEMS FOR ORAL CARE PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 1998-06-04 WO claimed
WO-1998002257-A1 IMPROVED ANTI-GRAFFITI COATINGS AND METHOD OF GRAFFITI REMOVAL BRANDEIS UNIVERSITY (US) 1998-01-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080008665-A1 Flavors for oral compositions TAS2R20, TAS2R10, TAS2R16 KMT2A 634/4885SMN1; SMN2 474/4885ESR1 2930/4885
US-10702460-B2 Method of protecting teeth against erosion SOD3, CA3, CTSA KMT2A 3263/4885SMN1; SMN2 1380/4885ESR1 3552/4885
US-20200038298-A1 Method Of Protecting Teeth Against Erosion SOD3, CA3, CTSA KMT2A 3263/4885SMN1; SMN2 1380/4885ESR1 3552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.