Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GMNN | O75496 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2995885 | 0.94 | LMNA (0.44) | LMNASMN1; SMN2CYP1A2MEN1KMT2A | |
| SCHEMBL9574228 | 0.92 | LMNA (0.42) | LMNASMN1; SMN2CYP1A2MEN1KMT2A | |
| SCHEMBL9634318 | 0.88 | MEN1 (0.50) | CYP1A2MEN1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL2201976 | 0.88 | MEN1 (0.50) | CYP1A2MEN1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL10382406 | 0.85 | KMT2A (0.51) | SMN1; SMN2CYP1A2MEN1KMT2ASLC1A3 | |
| Perchlorate SCHEMBL9634002 | 0.83 | MEN1 (0.46) | CYP1A2MEN1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL17303194 | 0.83 | MEN1 (0.46) | CYP1A2MEN1KMT2ASLC1A3SLC1A2 | |
| Perchlorate SCHEMBL9633990 | 0.83 | MEN1 (0.46) | CYP1A2MEN1KMT2ASLC1A3SLC1A2 | |
| SCHEMBL28790050 | 0.82 | SLC1A3 (0.46) | SMN1; SMN2CYP1A2MEN1KMT2ASLC1A3 | |
| SCHEMBL12136516 | 0.82 | SLC1A3 (0.46) | SMN1; SMN2CYP1A2MEN1KMT2ASLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107519496-B | L-carnitine amphiphilic derivative, nanoparticle modified by same and application thereof | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2019-12-10 | — | — | CN | claimed |
| CN-107176911-B | Oral targeted nano granule based on intestinal epithelial cell top side OCTN2 transporter | 沈阳药科大学 | 2019-07-26 | — | — | CN | claimed |
| CN-107519496-B | L-carnitine amphiphilic derivative, nanoparticle modified by same and application thereof | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2019-12-10 | — | — | CN | disclosed |