Tetrabuthylammonium

Tetrabuthylammonium

SCHEMBL28314916

CCCC[N+](CCCC)(CCCC)CCCC.CCCC[Si](c1ccccc1)c1ccccc1.[F-]

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A1 O15245 3/20 0.43
DNM1 Q05193 4/20 0.39
SLC22A2 O15244 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
TP53 P04637 2/20 0.38
MAPK1 P28482 2/20 0.38
HTT P42858 3/20 0.37
ALDH1A1 P00352 2/20 0.35
CYP3A4 P08684 2/20 0.35
HIF1A Q16665 2/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
ALOX12 P18054 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MLNR O43193 1/20 0.35
NR1I2 O75469 1/20 0.35
ESR1 P03372 1/20 0.35
NR3C1 P04150 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL114778 0.87 LTA4H (0.38) DNM1SMN1; SMN2MEN1KMT2ATP53
Hydrochloric Acid SCHEMBL27842651 0.85 LTA4H (0.36) DNM1SMN1; SMN2MEN1KMT2ATP53
SCHEMBL416284 0.85 LTA4H (0.38) DNM1SMN1; SMN2MEN1KMT2ATP53
SCHEMBL5973636 0.83 DNM1 (0.40) DNM1SMN1; SMN2MEN1KMT2ATP53
SCHEMBL561210 0.83 DNM1 (0.40) DNM1SMN1; SMN2MEN1KMT2ATP53
SCHEMBL8992480 0.83 DNM1 (0.40) DNM1SMN1; SMN2MEN1KMT2ATP53
SCHEMBL8992135 0.83 DNM1 (0.40) DNM1SMN1; SMN2MEN1KMT2ATP53
Tetrabuthylammonium SCHEMBL20544167 0.81 SLC22A1 (0.50) SLC22A1DNM1SLC22A2SMN1; SMN2MEN1
Tetrabuthylammonium SCHEMBL27636521 0.78 SLC22A1 (0.46) SLC22A1DNM1SLC22A2SMN1; SMN2MEN1
SCHEMBL415334 0.74 TP53 (0.38) MEN1KMT2ATP53ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106866645-B A method of Kan Gelie piperazine is prepared using microreactor one kettle way continuous flow 齐鲁天和惠世制药有限公司 2019-07-23 CN disclosed