Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.30 |
| ▸ | CA1 | P00915 | 3/20 | 0.30 |
| ▸ | CA2 | P00918 | 3/20 | 0.30 |
| ▸ | CA7 | P43166 | 3/20 | 0.30 |
| ▸ | CA9 | Q16790 | 3/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42014 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL1339076 | 0.84 | — | — | |
| Water SCHEMBL27757227 | 0.84 | — | — | |
| Ethylene SCHEMBL31472583 | 0.81 | — | — | |
| Bicarbonate SCHEMBL28442958 | 0.81 | TSHR (0.48) | TSHRHCAR2CA12CA1CA2 | |
| Ethoxycarbonyl Group SCHEMBL28313656 | 0.78 | TSHR (0.36) | TSHRHCAR2LMNA | |
| SCHEMBL28144012 | 0.75 | TSHR (0.42) | TSHRHCAR2CA12CA1CA2 | |
| Hexane SCHEMBL28267578 | 0.73 | LMNA (0.57) | TSHRCA1LMNA | |
| SCHEMBL28876509 | 0.72 | TSHR (0.43) | TSHRHCAR2CA12CA1CA2 | |
| Isopropyl Alcohol SCHEMBL18815431 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177786-A | Pyrazolo [1,5-A] pyridine compounds being substituted are as RET kinase inhibitor | 阿雷生物药品公司 | 2019-08-27 | — | — | CN | disclosed |