Ethoxycarbonyl Group

Ethoxycarbonyl Group

SCHEMBL28313656

CC(C)OC(=O)Cl.CCOC=O

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
LMNA P02545 2/20 0.34
HCAR2 Q8TDS4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethoxycarbonyl Group SCHEMBL7636773 0.80
SCHEMBL42014 0.79
SCHEMBL9238281 0.78 ALDH1A1 (0.40) TSHRLMNAHCAR2
Ethoxycarbonyl Group SCHEMBL28000975 0.78 TSHR (0.36) TSHRLMNA
Formic Acid Methyl Ester SCHEMBL28314928 0.78 TSHR (0.42) TSHRLMNAHCAR2
Oxalic Acid SCHEMBL28209539 0.77 HCAR2 (0.36) LMNAHCAR2
Ethoxycarbonyl Group SCHEMBL17825894 0.77
Hydrochloric Acid SCHEMBL1339076 0.77
Water SCHEMBL27757227 0.77
Hexane SCHEMBL28267578 0.76 LMNA (0.57) TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110177786-A Pyrazolo [1,5-A] pyridine compounds being substituted are as RET kinase inhibitor 阿雷生物药品公司 2019-08-27 CN disclosed