Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.41 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4018256 | 0.84 | KMT2A (0.43) | BACE1NR1D1KDM4EALDH1A1HPGD | |
| SCHEMBL28150917 | 0.84 | KDM4E (0.42) | BACE1NR1D1KDM4EALDH1A1PPARG | |
| SCHEMBL28315356 | 0.81 | KDM4E (0.52) | FDFT1KDM4EALDH1A1 | |
| SCHEMBL28151812 | 0.80 | KDM4E (0.48) | KDM4EALDH1A1 | |
| SCHEMBL28151823 | 0.79 | KDM4E (0.48) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL28150930 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1HPGDPOLBGAA | |
| SCHEMBL28313934 | 0.78 | KDM4E (0.47) | ACHEKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL28150972 | 0.77 | KDM4E (0.46) | ACHEKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL4018252 | 0.75 | KMT2A (0.39) | BACE1NR1D1KDM4EALDH1A1POLB | |
| SCHEMBL2525569 | 0.74 | BACE1 (0.47) | BACE1NR1D1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715414-B | With 2 adrenaline excitant of β and the active new bicyclic derivatives of M3 muscarinic antagonist | 阿尔米雷尔有限公司 | 2019-08-30 | — | — | CN | disclosed |