Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28315299 | 0.84 | ACHE (0.43) | KMT2APOLBGAAKDM4EALDH1A1 | |
| SCHEMBL4018252 | 0.82 | KMT2A (0.39) | KMT2APOLBGAACACNA1BAPBA1 | |
| SCHEMBL4016945 | 0.82 | ALDH1A1 (0.53) | KMT2ACACNA1BALDH1A1MAPTTDP1 | |
| SCHEMBL2525569 | 0.81 | BACE1 (0.47) | KMT2APOLBGAACACNA1BAPBA1 | |
| SCHEMBL28151828 | 0.81 | POLB (0.44) | KMT2APOLBGAACACNA1BAPBA1 | |
| SCHEMBL15580586 | 0.78 | KMT2A (0.54) | KMT2APOLBGAACACNA1BAPBA1 | |
| SCHEMBL18020598 | 0.76 | KMT2A (0.57) | KMT2APOLBGAACACNA1BAPBA1 | |
| SCHEMBL7458715 | 0.76 | MLYCD (0.50) | KMT2ALTB4RLTB4R2 | |
| SCHEMBL30264517 | 0.75 | AOC3 (0.51) | KMT2AGAAALDH1A1MEN1 | |
| SCHEMBL3014165 | 0.74 | LTB4R (0.67) | LTB4RLTB4R2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009092796-A1 | SYNEPHRINE DERIVATIVES FOR THE TREATMENT OF CANCER | UNIVERSITEIT GENT (BE) | 2009-07-30 | — | — | WO | disclosed |