Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4016939 | 0.82 | KMT2A (0.52) | KMT2AGAAMAPTALDH1A1TDP1 | |
| SCHEMBL4018256 | 0.82 | KMT2A (0.43) | KMT2AGAAPOLBMAPTALDH1A1 | |
| SCHEMBL2525569 | 0.80 | BACE1 (0.47) | KMT2AGAAPOLBMAPTALDH1A1 | |
| SCHEMBL28315299 | 0.75 | ACHE (0.43) | KMT2AGAAPOLBALDH1A1NR1D1 | |
| SCHEMBL27604498 | 0.72 | KMT2A (0.43) | KMT2AGAAPOLBALDH1A1ADRB2 | |
| SCHEMBL2529414 | 0.71 | AURKA (0.38) | MAPTALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL28151828 | 0.71 | POLB (0.44) | KMT2AGAAPOLBMAPTALDH1A1 | |
| SCHEMBL974720 | 0.71 | NR4A1 (0.53) | KMT2AGAAPOLBMAPTALDH1A1 | |
| SCHEMBL18020598 | 0.70 | KMT2A (0.57) | KMT2AGAAPOLBMAPTALDH1A1 | |
| SCHEMBL28813458 | 0.70 | CACNA1B (0.59) | KMT2AGAAPOLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009092796-A1 | SYNEPHRINE DERIVATIVES FOR THE TREATMENT OF CANCER | UNIVERSITEIT GENT (BE) | 2009-07-30 | — | — | WO | disclosed |