SCHEMBL28315399

SCHEMBL28315399

CC(C)(O)c1ccc(C2(S(=O)(=O)c3ccc(F)cc3)CCCC2)cc1

nearest known ligand 0.79

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RORC P51449 20/20 0.79
NR1I2 O75469 9/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16880281 0.88 RORC (1.00) RORCNR1I2
SCHEMBL28876112 0.87 RORC (0.72) RORCNR1I2
SCHEMBL16880409 0.85 RORC (1.00) RORCNR1I2
SCHEMBL16880323 0.85 RORC (1.00) RORCNR1I2
SCHEMBL16888206 0.84 RORC (0.97) RORCNR1I2
SCHEMBL16891643 0.83 RORC (1.00) RORCNR1I2
SCHEMBL16891743 0.83 RORC (0.95) RORCNR1I2
SCHEMBL16880322 0.82 RORC (1.00) RORCNR1I2
SCHEMBL16880561 0.82 RORC (1.00) RORCNR1I2
SCHEMBL16891642 0.81 RORC (1.00) RORCNR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106132931-B Carbocyclic ring sulfone ROR gamma modulators 百时美施贵宝公司 2019-08-02 CN disclosed