Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL759159 | 0.87 | TSHR (0.42) | TSHRTHRBTBXAS1NAAAPOLB | |
| SCHEMBL6363350 | 0.83 | TSHR (0.38) | TSHRTHRBTBXAS1POLBAPEX1 | |
| SCHEMBL6547122 | 0.81 | TSHR (0.56) | TSHRTHRBTBXAS1POLBAPEX1 | |
| SCHEMBL8773672 | 0.81 | TSHR (0.51) | TSHRTHRBTDP1ALDH1A1 | |
| SCHEMBL6911790 | 0.79 | TSHR (0.37) | TSHRTHRBTBXAS1POLBAPEX1 | |
| SCHEMBL406198 | 0.77 | ALDH1A1 (0.50) | TSHRTBXAS1POLBAPEX1HTT | |
| SCHEMBL7051658 | 0.77 | TSHR (0.56) | TSHRTHRBNAAAALDH1A1HCAR2 | |
| SCHEMBL1648944 | 0.76 | TBXAS1 (0.37) | TSHRTBXAS1 | |
| SCHEMBL8846029 | 0.76 | TSHR (0.59) | TSHRTHRBTBXAS1POLBAPEX1 | |
| SCHEMBL5590452 | 0.76 | TSHR (0.34) | TSHRTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1935956-B1 | USE OF REPULPABLE PRESSURE-SENSITIVE ADHESIVES FOR BONDING OF PAPER COMPRISING CALCIUM(II) IONS | TESA SE (DE) | 2017-02-08 | — | — | EP | disclosed |
| EP-2166051-B1 | REPULPABLE ADHESIVE | TESA SE (DE) | 2016-08-24 | — | — | EP | disclosed |
| EP-2166051-A1 | Repulpable adhesive | tesa SE (DE) | 2010-03-24 | — | — | EP | disclosed |
| EP-1935956-A2 | Repulpable adhesive | Tesa AG (DE) | 2008-06-25 | — | — | EP | disclosed |