Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | ALKBH2 | Q6NS38 | 2/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | ALKBH1 | Q13686 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31681673 | 0.83 | L3MBTL1 (0.67) | L3MBTL1ALKBH2HPGDSHSD17B10EGLN1 | |
| SCHEMBL16597309 | 0.82 | L3MBTL1 (0.43) | L3MBTL1ACHE | |
| SCHEMBL29954606 | 0.82 | L3MBTL1 (0.65) | L3MBTL1ALKBH2HPGDSHSD17B10EGLN1 | |
| SCHEMBL28578166 | 0.80 | L3MBTL1 (0.62) | L3MBTL1ALKBH2HPGDSHSD17B10EGLN1 | |
| SCHEMBL4022892 | 0.80 | L3MBTL1 (0.62) | L3MBTL1ALKBH2HPGDSHSD17B10EGLN1 | |
| SCHEMBL553834 | 0.80 | L3MBTL1 (0.73) | L3MBTL1ALKBH2HPGDSHSD17B10EGLN1 | |
| SCHEMBL4900355 | 0.80 | L3MBTL1 (0.62) | L3MBTL1ALKBH2HPGDSHSD17B10EGLN1 | |
| SCHEMBL18038382 | 0.78 | L3MBTL1 (0.71) | L3MBTL1ALKBH2HPGDSHSD17B10EGLN1 | |
| Hydrochloric Acid SCHEMBL4758885 | 0.78 | L3MBTL1 (0.71) | L3MBTL1ALKBH2HPGDSHSD17B10EGLN1 | |
| SCHEMBL31286462 | 0.77 | L3MBTL1 (0.69) | L3MBTL1ALKBH2HPGDSHSD17B10EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110072863-A | RIP1 kinase inhibitors and methods of use | 豪夫迈·罗氏有限公司 | 2019-07-30 | — | — | CN | disclosed |