Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | ALKBH2 | Q6NS38 | 2/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | ALKBH1 | Q13686 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12804394 | 0.85 | L3MBTL1 (0.69) | L3MBTL1ALKBH2HPGDSACHEHSD17B10 | |
| SCHEMBL28578166 | 0.84 | L3MBTL1 (0.62) | L3MBTL1ALKBH2HPGDSACHEHSD17B10 | |
| SCHEMBL31681673 | 0.83 | L3MBTL1 (0.67) | L3MBTL1ALKBH2HPGDSACHEHSD17B10 | |
| SCHEMBL18281349 | 0.82 | L3MBTL1 (0.43) | L3MBTL1ACHE | |
| SCHEMBL29954606 | 0.82 | L3MBTL1 (0.65) | L3MBTL1ALKBH2HPGDSACHEHSD17B10 | |
| SCHEMBL27806602 | 0.81 | L3MBTL1 (0.59) | L3MBTL1ALKBH2HPGDSACHEHSD17B10 | |
| SCHEMBL4900355 | 0.80 | L3MBTL1 (0.62) | L3MBTL1ALKBH2HPGDSACHEHSD17B10 | |
| SCHEMBL553834 | 0.80 | L3MBTL1 (0.73) | L3MBTL1ALKBH2HPGDSACHEHSD17B10 | |
| SCHEMBL28316059 | 0.80 | L3MBTL1 (0.62) | L3MBTL1ALKBH2HPGDSACHEHSD17B10 | |
| SCHEMBL30535495 | 0.79 | L3MBTL1 (0.67) | L3MBTL1ALKBH2HPGDSACHEHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8759345-B2 | Benzoimidazoles as prolyl hydroxylase inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2014-06-24 | — | — | US | disclosed |
| EP-2057126-A2 | PROCESS FOR PREPARING 3-DIHALOMETHYLPYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008022777-A2 | PROCESS FOR PREPARING 3-DIHALOMETHYLPYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-02-28 | — | — | WO | disclosed |