Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.44 |
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL163939 | 0.87 | TDP1 (0.56) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL28283115 | 0.87 | TDP1 (0.56) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL27519979 | 0.85 | TDP1 (0.54) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Bromide SCHEMBL8414921 | 0.85 | TDP1 (0.54) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL27996952 | 0.85 | TDP1 (0.54) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Alcohol SCHEMBL28915598 | 0.84 | PGR (0.55) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL1792142 | 0.83 | TDP1 (0.52) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL1792144 | 0.83 | TDP1 (0.52) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Acetic Acid SCHEMBL28771195 | 0.83 | TDP1 (0.52) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Formaldehyde SCHEMBL10644284 | 0.83 | TDP1 (0.52) | PGRADRA2AADRA2BHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110078594-A | A kind of synthetic method of p-hydroxyphenylethanol | 新昌县泰如科技有限公司 | 2019-08-02 | — | — | CN | disclosed |