Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8660520 | 0.87 | SIGMAR1 (0.47) | SIGMAR1CYP2C19MEN1KMT2AHRH3 | |
| SCHEMBL28071023 | 0.71 | POLB (0.31) | — | |
| SCHEMBL1243297 | 0.71 | HPGD (0.41) | CYP2C19MEN1KMT2ACYP2D6SLC6A4 | |
| SCHEMBL759019 | 0.69 | SIGMAR1 (0.66) | SIGMAR1CYP2C19CXCR4USP2MEN1 | |
| SCHEMBL10498523 | 0.67 | DPP4 (0.32) | — | |
| SCHEMBL29045055 | 0.67 | — | — | |
| SCHEMBL11558246 | 0.66 | SIGMAR1 (0.51) | SIGMAR1CYP2C19MEN1KMT2ASLC6A2 | |
| SCHEMBL4630092 | 0.65 | MAPT (0.39) | MEN1KMT2A | |
| SCHEMBL28444623 | 0.65 | LTA4H (0.51) | SIGMAR1HRH3 | |
| SCHEMBL27705364 | 0.64 | SIGMAR1 (0.53) | SIGMAR1CYP2C19MEN1KMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023312-A | The Compounds and methods for for preventing malarial parasite from propagating | 由卫生与公众服务部部长代表的美利坚合众国 | 2019-07-16 | — | — | CN | disclosed |