Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | MDH1 | P40925 | 10/20 | 0.43 |
| ▸ | MDH2 | P40926 | 10/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31151825 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP3A4SHBGMDH1MDH2 | |
| Hydrochloric Acid SCHEMBL10387366 | 0.79 | SMN1; SMN2 (0.52) | SMN1; SMN2CYP3A4SHBGMDH1MDH2 | |
| SCHEMBL152841 | 0.79 | CYP2C19 (0.46) | SMN1; SMN2CYP3A4SHBGPPARA | |
| SCHEMBL10387363 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2CYP3A4SHBGMDH1MDH2 | |
| SCHEMBL8563107 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP3A4SHBGMDH1MDH2 | |
| SCHEMBL8563110 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP3A4SHBGMDH1MDH2 | |
| SCHEMBL28761267 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP3A4SHBGMDH1MDH2 | |
| SCHEMBL4619376 | 0.76 | CYP3A4 (0.56) | SMN1; SMN2CYP3A4SHBGMDH1MDH2 | |
| SCHEMBL9237163 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP3A4SHBGMDH1MDH2 | |
| SCHEMBL9237158 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP3A4SHBGMDH1MDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110105434-A | The polypeptide and application thereof of stitching and suture | 哈佛大学的校长及成员们 | 2019-08-09 | — | — | CN | disclosed |