Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | MDH1 | P40925 | 10/20 | 0.39 |
| ▸ | MDH2 | P40926 | 10/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9237163 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP3A4SHBGMDH1MDH2 | |
| SCHEMBL9238802 | 0.81 | PPARG (0.50) | SLC1A2KIF11 | |
| SCHEMBL9238806 | 0.81 | PPARG (0.50) | SLC1A2KIF11 | |
| SCHEMBL9236830 | 0.79 | PPARG (0.43) | SLC1A2KIF11 | |
| SCHEMBL9241984 | 0.79 | PPARG (0.47) | SLC1A2KIF11 | |
| SCHEMBL9236828 | 0.79 | PPARG (0.43) | SLC1A2KIF11 | |
| SCHEMBL9241636 | 0.77 | KMT2A (0.44) | SMN1; SMN2SLC1A2 | |
| SCHEMBL9241640 | 0.77 | KMT2A (0.44) | SMN1; SMN2SLC1A2 | |
| SCHEMBL9238607 | 0.77 | KMT2A (0.47) | SMN1; SMN2 | |
| SCHEMBL9238609 | 0.77 | KMT2A (0.47) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658539-A1 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1995-06-21 | — | — | EP | disclosed |