Toluene

Toluene

SCHEMBL28317833

Cc1ccccc1.N#CCc1cccs1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 2/20 0.47
CTSC P53634 1/20 0.42
LMNA P02545 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
HPGD P15428 4/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
GAA P10253 1/20 0.41
TRPM8 Q7Z2W7 3/20 0.40
TSHR P16473 1/20 0.39
ALOX12 P18054 1/20 0.39
ACHE P22303 1/20 0.39
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37659 0.87
Pyridine SCHEMBL28967270 0.80 CTSC (0.40) SLC6A3CTSCMEN1KMT2AHPGD
Toluene SCHEMBL15303842 0.75 LMNA (0.48) LMNAKMT2ASMN1; SMN2NPC1RAB9A
Toluene SCHEMBL15756043 0.75 LMNA (0.48) LMNAKMT2ASMN1; SMN2NPC1RAB9A
Toluene SCHEMBL15756051 0.75 LMNA (0.48) LMNAKMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL7878372 0.72 DRD2 (0.48) SLC6A3CTSCLMNAKDM4E
SCHEMBL3385419 0.69 MEN1 (0.54) SLC6A3LMNAMEN1KMT2AHPGD
Toluene SCHEMBL28200585 0.69 TSHR (0.58) LMNAMEN1KMT2AHPGDSMN1; SMN2
Toluene SCHEMBL9712043 0.69 TSHR (0.58) LMNAMEN1KMT2AHPGDSMN1; SMN2
Toluene SCHEMBL11841496 0.68 TSHR (0.55) LMNAMEN1KMT2AHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110194765-A For controlling the composition and method of nematode 孟山都技术有限公司 2019-09-03 CN disclosed