⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28321164 | 0.98 | LMNA (0.31) | — | |
| SCHEMBL29103538 | 0.76 | TP53 (0.30) | — | |
| SCHEMBL133569 | 0.70 | — | — | |
| SCHEMBL1759161 | 0.70 | — | — | |
| SCHEMBL13140760 | 0.70 | TSHR (0.39) | — | |
| Ammonia Solution, Strong SCHEMBL6052085 | 0.69 | — | — | |
| SCHEMBL16618909 | 0.65 | — | — | |
| SCHEMBL17204228 | 0.65 | — | — | |
| SCHEMBL3914975 | 0.64 | TSHR (0.33) | — | |
| SCHEMBL14594120 | 0.64 | TSHR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250109148-A1 | HETEROCYCLIC GLP-1 AGONISTS | SHANGHAI SHOUTI BIOTECHNOLOGY CO., LTD. (CN) | 2025-04-03 | — | — | US | disclosed |
| WO-2023245137-A1 | SLOW SKELETAL TROPONIN ACTIVATORS | CYTOKINETICS, INCORPORATED (US) | 2023-12-21 | — | — | WO | disclosed |
| EP-4271674-A1 | CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-11-08 | — | — | EP | disclosed |
| WO-2022225914-A1 | CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-10-27 | — | — | WO | disclosed |
| CN-110114351-A | The heterocycle inhibitor of MCT4 | 维托尔股份有限公司 | 2019-08-09 | — | — | CN | disclosed |