Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8206910 | 0.93 | — | — | |
| Acetic Acid SCHEMBL29046887 | 0.93 | CA1 (0.57) | CA1CA4LMNATDP1TSHR | |
| Acetic Acid SCHEMBL27897081 | 0.93 | CA1 (0.57) | CA1CA4LMNATDP1TSHR | |
| Acetic Acid SCHEMBL2186272 | 0.93 | CA1 (0.64) | CA1CA4LMNATDP1TSHR | |
| Acetic Acid SCHEMBL17747086 | 0.93 | CA1 (0.57) | CA1CA4LMNATDP1TSHR | |
| Acetic Acid SCHEMBL28420347 | 0.93 | CA1 (0.57) | CA1CA4LMNATDP1TSHR | |
| Acetic Acid SCHEMBL3173468 | 0.93 | — | — | |
| Acetic Acid SCHEMBL10534378 | 0.90 | CA1 (0.60) | CA1CA4LMNATDP1FFAR3 | |
| Acetic Acid SCHEMBL27972026 | 0.90 | CA1 (0.60) | CA1CA4LMNATDP1FFAR3 | |
| Acetic Acid SCHEMBL30191091 | 0.87 | CA1 (0.50) | CA1CA4FFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114177944-A | Visible light catalytic degradation anabasine pesticide of metal organic framework compound | 北京农学院 | 2022-03-15 | — | — | CN | claimed |
| CN-108114750-B | A kind of Pd/UiO-66-NH2Composite material and preparation method and application | 辽宁大学 | 2019-09-13 | — | — | CN | claimed |
| CN-116577314-A | Method for eliminating impurity peak of silver-based surface enhanced Raman substrate and trace detection method | 清华大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-114177944-A | Visible light catalytic degradation anabasine pesticide of metal organic framework compound | 北京农学院 | 2022-03-15 | — | — | CN | disclosed |
| CN-111333853-A | Preparation method of composite material based on MOF @ metal nanoparticles @ COF | 北京科技大学 | 2020-06-26 | — | — | CN | disclosed |