Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2186272 | 1.00 | CA1 (0.64) | — | |
| Acetic Acid SCHEMBL3173468 | 1.00 | — | — | |
| Acetic Acid SCHEMBL27972026 | 0.97 | CA1 (0.60) | — | |
| Acetic Acid SCHEMBL10534378 | 0.97 | CA1 (0.60) | — | |
| Acetic Acid SCHEMBL28015778 | 0.94 | CA1 (0.56) | — | |
| Acetic Acid SCHEMBL29046887 | 0.93 | CA1 (0.57) | — | |
| Acetic Acid SCHEMBL28420347 | 0.93 | CA1 (0.57) | — | |
| Acetic Acid SCHEMBL27897081 | 0.93 | CA1 (0.57) | — | |
| Acetic Acid SCHEMBL17747086 | 0.93 | CA1 (0.57) | — | |
| Acetic Acid SCHEMBL28318641 | 0.93 | CA1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708627-B1 | METHOD AND DEVICE FOR PROVIDING NICOTINE REPLACEMENT THERAPY TRANSDERMALLY/TRANSBUCCALLY | CYGNUS THERAPEUTIC SYSTEMS (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0708627-A4 | METHOD AND DEVICE FOR PROVIDING NICOTINE REPLACEMENT THERAPY TRANSDERMALLY/TRANSBUCCALLY | CYGNUS THERAPEUTIC SYSTEMS (US) | 1997-04-23 | — | — | EP | disclosed |
| EP-0708627-A1 | METHOD AND DEVICE FOR PROVIDING NICOTINE REPLACEMENT THERAPY TRANSDERMALLY/TRANSBUCCALLY | CYGNUS, INC. (US) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995001766-A1 | METHOD AND DEVICE FOR PROVIDING NICOTINE REPLACEMENT THERAPY TRANSDERMALLY/TRANSBUCCALLY | CYGNUS THERAPEUTIC SYSTEMS (US) | 1995-01-19 | — | — | WO | disclosed |