Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.58 |
| ▸ | MMP9 | P14780 | 5/20 | 0.58 |
| ▸ | MAOB | P27338 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL982499 | 0.81 | MAPK1 (0.75) | MAOAMMP9MAOBKDM4EALDH1A1 | |
| SCHEMBL979729 | 0.74 | MAPK1 (0.68) | MAOAMMP9MAOBKDM4EALDH1A1 | |
| SCHEMBL28490940 | 0.74 | HDAC6 (0.63) | MAOAMMP9MAOBKDM4EALDH1A1 | |
| SCHEMBL985091 | 0.73 | MAPK1 (0.66) | MAOAMMP9MAOBKDM4EALDH1A1 | |
| SCHEMBL2831902 | 0.71 | MAOA (0.51) | MAOAMMP9MAOBKDM4EALDH1A1 | |
| SCHEMBL13844736 | 0.69 | KDM4E (0.73) | MAOAMMP9MAOBKDM4EALDH1A1 | |
| SCHEMBL981898 | 0.67 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10PDE4D | |
| SCHEMBL3910855 | 0.67 | MAOA (0.52) | MAOAMMP9MAOBKDM4EALDH1A1 | |
| SCHEMBL18691769 | 0.65 | PDE4D (0.49) | MAOAMMP9MAOBKDM4EALDH1A1 | |
| SCHEMBL980624 | 0.65 | KDM4E (0.77) | KDM4EALDH1A1HPGDHSD17B10PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6239747-A | — | — | None | — | — | JP | disclosed |
| JP-6239747-A | — | — | None | — | — | JP | disclosed |
| EP-1009316-B1 | APPARATUS AND METHOD FOR AN AUDITORY STIMULATOR | BAUMAN NATAN (US) | 2013-10-09 | — | — | EP | disclosed |
| US-20100209537-A1 | Metal complexes with anticancer activity | BANGALORE RAMESH | 2010-08-19 | — | — | US | disclosed |
| US-6048305-A | Apparatus and method for an open ear auditory pathway stimulator to manage tinnitus and hyperacusis | NATAN BAUMAN (US) | 2000-04-11 | — | — | US | disclosed |
| EP-0542689-B1 | Use of 1-(aminoalkyl)-3-quinoxaline-2-on derivatives for the preparation of neuroprotective compositions | PHAFAG AG (LI) | 1998-09-23 | — | — | EP | disclosed |
| US-5563140-A | Use of 1-(aminoalkyl)-3-(benzyl)-quinoxaline-2-one derivatives for the preparation of neuroprotective compositions | PHAFAG AKTIENGESELLSCHAFT (LI) | 1996-10-08 | — | — | US | disclosed |
| US-5563140-A | Use of 1-(aminoalkyl)-3-(benzyl)-quinoxaline-2-one derivatives for the preparation of neuroprotective compositions | PHAFAG AKTIENGESELLSCHAFT (LI) | 1996-10-08 | — | — | US | disclosed |
| JP-H06239747-A | METHOD FOR USING 1-(AMINOALKYL)-3-(BENZYL)-QUINOXALINE-2-ONE DERIVATIVE FOR PREPARING NERVEPROTECTIVE COMPOSITION | PHAFAG AG | 1994-08-30 | — | — | JP | disclosed |
| JP-H06239747-A | METHOD FOR USING 1-(AMINOALKYL)-3-(BENZYL)-QUINOXALINE-2-ONE DERIVATIVE FOR PREPARING NERVEPROTECTIVE COMPOSITION | PHAFAG AG | 1994-08-30 | — | — | JP | disclosed |
| EP-0542689-A1 | Use of 1-(aminoalkyl)-3-quinoxaline-2-on derivatives for the preparation of neuroprotective compositions | PHAFAG AKTIENGESELLSCHAFT (LI) | 1993-05-19 | — | — | EP | disclosed |