Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.51 |
| ▸ | MAOB | P27338 | 6/20 | 0.51 |
| ▸ | MMP9 | P14780 | 5/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1969712 | 0.80 | ALDH1A1 (0.45) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL7513852 | 0.77 | OGFRL1 (0.43) | ALDH1A1HTTMAPK1 | |
| SCHEMBL28490940 | 0.73 | HDAC6 (0.63) | MAOAMAOBMMP9PTPN1PDE4A | |
| SCHEMBL982499 | 0.72 | MAPK1 (0.75) | MAOAMAOBMMP9PTPN1PDE4A | |
| SCHEMBL2831908 | 0.71 | MAOA (0.58) | MAOAMAOBMMP9PTPN1PDE4A | |
| SCHEMBL10342549 | 0.70 | TSHR (0.52) | — | |
| SCHEMBL11873127 | 0.69 | HSD17B10 (0.65) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL3903902 | 0.66 | PDE4D (0.46) | MAOAMAOBMMP9PDE4APDE4B | |
| SCHEMBL10668761 | 0.65 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL979729 | 0.65 | MAPK1 (0.68) | MAOAMAOBMMP9PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6239747-A | — | — | None | — | — | JP | disclosed |
| JP-6239747-A | — | — | None | — | — | JP | disclosed |
| EP-1009316-B1 | APPARATUS AND METHOD FOR AN AUDITORY STIMULATOR | BAUMAN NATAN (US) | 2013-10-09 | — | — | EP | disclosed |
| US-20100209537-A1 | Metal complexes with anticancer activity | BANGALORE RAMESH | 2010-08-19 | — | — | US | disclosed |
| EP-1009316-A4 | APPARATUS AND METHOD FOR AN AUDITORY STIMULATOR | BAUMAN NATAN (US) | 2008-11-19 | — | — | EP | disclosed |
| EP-1009316-A1 | APPARATUS AND METHOD FOR AN AUDITORY STIMULATOR | Bauman, Natan (US) | 2000-06-21 | — | — | EP | disclosed |
| US-6048305-A | Apparatus and method for an open ear auditory pathway stimulator to manage tinnitus and hyperacusis | NATAN BAUMAN (US) | 2000-04-11 | — | — | US | disclosed |
| WO-1999007302-A1 | APPARATUS AND METHOD FOR AN AUDITORY STIMULATOR | BAUMAN NATAN (US) | 1999-02-18 | — | — | WO | disclosed |
| EP-0542689-B1 | Use of 1-(aminoalkyl)-3-quinoxaline-2-on derivatives for the preparation of neuroprotective compositions | PHAFAG AG (LI) | 1998-09-23 | — | — | EP | disclosed |
| US-5563140-A | Use of 1-(aminoalkyl)-3-(benzyl)-quinoxaline-2-one derivatives for the preparation of neuroprotective compositions | PHAFAG AKTIENGESELLSCHAFT (LI) | 1996-10-08 | — | — | US | disclosed |
| US-5563140-A | Use of 1-(aminoalkyl)-3-(benzyl)-quinoxaline-2-one derivatives for the preparation of neuroprotective compositions | PHAFAG AKTIENGESELLSCHAFT (LI) | 1996-10-08 | — | — | US | disclosed |
| JP-H06239747-A | METHOD FOR USING 1-(AMINOALKYL)-3-(BENZYL)-QUINOXALINE-2-ONE DERIVATIVE FOR PREPARING NERVEPROTECTIVE COMPOSITION | PHAFAG AG | 1994-08-30 | — | — | JP | disclosed |
| JP-H06239747-A | METHOD FOR USING 1-(AMINOALKYL)-3-(BENZYL)-QUINOXALINE-2-ONE DERIVATIVE FOR PREPARING NERVEPROTECTIVE COMPOSITION | PHAFAG AG | 1994-08-30 | — | — | JP | disclosed |
| EP-0542689-A1 | Use of 1-(aminoalkyl)-3-quinoxaline-2-on derivatives for the preparation of neuroprotective compositions | PHAFAG AKTIENGESELLSCHAFT (LI) | 1993-05-19 | — | — | EP | disclosed |