Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | CES1 | P23141 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrimidine SCHEMBL28161287 | 0.83 | L3MBTL1 (0.70) | POLBMAPK1L3MBTL1SRD5A2CES2 | |
| SCHEMBL8558988 | 0.81 | MEN1 (0.53) | POLBL3MBTL1GAALMNAMEN1 | |
| Pyridine SCHEMBL27374629 | 0.80 | L3MBTL1 (0.75) | POLBMAPK1L3MBTL1SRD5A2CES2 | |
| SCHEMBL28847269 | 0.80 | POLB (0.83) | POLBMAPK1L3MBTL1SRD5A2CES2 | |
| SCHEMBL14988297 | 0.80 | POLB (0.63) | POLBMAPK1L3MBTL1SRD5A2CES2 | |
| SCHEMBL229627 | 0.80 | POLB (0.82) | POLBMAPK1L3MBTL1SRD5A2CES2 | |
| Benzophenone SCHEMBL28231509 | 0.80 | POLB (0.82) | POLBMAPK1L3MBTL1SRD5A2CES2 | |
| SCHEMBL16690235 | 0.78 | POLB (0.93) | POLBMAPK1L3MBTL1SRD5A2CES2 | |
| SCHEMBL9805952 | 0.78 | POLB (1.00) | POLBMAPK1L3MBTL1SRD5A2CES2 | |
| Methane SCHEMBL29286698 | 0.78 | POLB (0.79) | POLBMAPK1L3MBTL1SRD5A2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106496127-B | A kind of preparation method of polysubstituted pyrimidine | 苏州大学 | 2019-09-27 | — | — | CN | disclosed |