Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.78 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.76 |
| ▸ | CA12 | O43570 | 3/20 | 0.70 |
| ▸ | CA9 | Q16790 | 3/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.58 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.58 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5960098 | 0.93 | KEAP1 (0.76) | CYP19A1KEAP1CA12CA9CYP1A2 | |
| SCHEMBL407414 | 0.87 | KEAP1 (1.00) | KEAP1CA12CA9CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL3516799 | 0.85 | KEAP1 (0.96) | KEAP1CA12CA9CYP1A2CYP3A4 | |
| SCHEMBL12550095 | 0.84 | KEAP1 (0.79) | KEAP1CA12CA9CYP1A2CYP3A4 | |
| SCHEMBL3915476 | 0.83 | PRMT1 (0.71) | ALDH1A1CA1CA2POLBPRMT1 | |
| SCHEMBL3925035 | 0.83 | CA12 (0.71) | CYP19A1CA12CA9CYP1A2CYP3A4 | |
| SCHEMBL28836818 | 0.83 | CA1 (0.73) | CYP19A1KEAP1CA12CA9CYP3A4 | |
| SCHEMBL5960052 | 0.83 | CA12 (0.71) | CYP19A1CA12CA9CYP1A2CYP3A4 | |
| SCHEMBL20946457 | 0.83 | CYP19A1 (0.69) | CYP19A1KEAP1CA12CA9CYP1A2 | |
| SCHEMBL3923271 | 0.83 | SMN1; SMN2 (0.71) | CYP19A1CYP1A2CYP3A4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110950784-A | P-cyclopropyl-N-benzyl benzene sulfonamide and synthesis preparation thereof | 郑州轻工业大学 | 2020-04-03 | — | — | CN | claimed |
| CN-1901902-A | Thiophene and benzothiophene hydroxamic acid derivatives | ATON PHARMA INC (US) | 2007-01-24 | — | — | CN | claimed |
| WO-2024186839-A1 | BICYCLIC ARYL SULFONAMIDES, SULFONES, AND SULFONATE ESTERS AS ANTI-PARASITIC AGENTS | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2024-09-12 | — | — | WO | disclosed |
| CN-118344268-A | Synthesis method of N-alkyl sulfonamide | 四川轻化工大学 | 2024-07-16 | — | — | CN | disclosed |
| CN-112047865-B | Method for synthesizing N-alkyl sulfonamide in water | 南京理工大学 | 2022-12-02 | — | — | CN | disclosed |
| CN-112047865-A | Method for synthesizing N-alkyl sulfonamide in water | 南京理工大学 | 2020-12-08 | — | — | CN | disclosed |
| CN-111056979-A | 3-cyclopropylbenzenesulfonyl benzylamine and synthesis method thereof | 郑州轻工业大学 | 2020-04-24 | — | — | CN | disclosed |
| CN-110950784-A | P-cyclopropyl-N-benzyl benzene sulfonamide and synthesis preparation thereof | 郑州轻工业大学 | 2020-04-03 | — | — | CN | disclosed |
| CN-110950784-A | P-cyclopropyl-N-benzyl benzene sulfonamide and synthesis preparation thereof | 郑州轻工业大学 | 2020-04-03 | — | — | CN | disclosed |
| EP-2976339-B1 | GEMINALLY SUBSTITUTED CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2018-06-27 | — | — | EP | disclosed |
| EP-2976339-B1 | GEMINALLY SUBSTITUTED CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2018-06-27 | — | — | EP | disclosed |
| US-5907068-A | TRIFLUOROMETHYLSUBSTITUTED COMPOUND INCLUDED IN PEPTIDES | ZENECA INC. (US) | 1999-05-25 | — | — | US | disclosed |
| US-5726158-A | INHIBITORS OF HUMAN LEUKOCYTE ELASTASE USEFUL IN TREATING TISSUE DEGENERATIVE DISEASES; TRIFLUOROMETHYL KETONE SUBSTITUTED DI-, TRI-, AND TETRA-PEPTIDE DERIVATIVES | ZENECA INC. (US) | 1998-03-10 | — | — | US | disclosed |
| US-5414132-A | Peptide intermediates | ZENECA INC. (US) | 1995-05-09 | — | — | US | disclosed |
| US-5194588-A | Inhibitors of human leukocyte elastase, di-, tri- and tetra-peptides | ICI AMERICAS INC. (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0189305-B1 | PEPTIDE DERIVATIVES | ICI AMERICAS INC. (US) | 1992-07-29 | — | — | EP | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| US-5055450-A | Di-, tri- and tetrapeptides as inhibitors of human leukocyte elastase | ICI AMERICAS INC. (US) | 1991-10-08 | — | — | US | disclosed |
| US-4910190-A | Containing a nitrogen containing heterocycle ring structure | ICI AMERICAS INC. (US) | 1990-03-20 | — | — | US | disclosed |
| EP-0189305-A2 | Peptide derivatives | ICI AMERICAS INC. (US) | 1986-07-30 | — | — | EP | disclosed |