Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28320126 | 0.86 | TP53 (0.47) | KDM4ESMN1; SMN2HSD17B10ALDH1A1LMNA | |
| SCHEMBL28320143 | 0.85 | F2 (0.38) | KDM4ESMN1; SMN2HSD17B10ALDH1A1LMNA | |
| SCHEMBL19506986 | 0.76 | APP (0.48) | APPLCKKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL12640272 | 0.75 | ALDH1A1 (0.41) | KDM4ESMN1; SMN2HSD17B10ALDH1A1LMNA | |
| SCHEMBL28247225 | 0.74 | LCK (0.52) | APPLCKKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL977779 | 0.73 | TP53 (0.49) | KDM4ESMN1; SMN2 | |
| SCHEMBL979646 | 0.72 | TP53 (0.48) | KDM4ELMNA | |
| SCHEMBL28048484 | 0.72 | MAPT (0.42) | KDM4ESMN1; SMN2HSD17B10ALDH1A1LMNA | |
| SCHEMBL21297072 | 0.72 | HDAC6 (0.38) | KDM4ESMN1; SMN2HSD17B10ALDH1A1LMNA | |
| SCHEMBL17182493 | 0.71 | ALDH1A1 (0.56) | KDM4ESMN1; SMN2HSD17B10ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106478619-B | A kind of xanthine oxidase inhibitor and its application | 江苏新元素医药科技有限公司 | 2019-09-24 | — | — | CN | disclosed |