Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12640272 | 0.84 | ALDH1A1 (0.41) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL25139543 | 0.76 | CYP2A6 (0.50) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL15623111 | 0.76 | ALDH1A1 (0.69) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL24169831 | 0.75 | ALDH1A1 (0.45) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL17182493 | 0.73 | ALDH1A1 (0.56) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL28048536 | 0.73 | PIM1 (0.60) | MAPTHTTALDH1A1KDM4EHPGD | |
| SCHEMBL12795524 | 0.73 | LMNA (0.51) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL28320126 | 0.73 | TP53 (0.47) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL977779 | 0.72 | TP53 (0.49) | KDM4ESMN1; SMN2RAB9ANPC1MAOB | |
| SCHEMBL24593388 | 0.72 | MAOB (0.50) | ALDH1A1KDM4EHPGDLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103450125-B | A kind of 5-replaces the synthetic method of benzofuran-2-carboxylic acid and derivative thereof | CHIMICA LABORATORIES CO., LTD. (CN) | 2016-01-13 | — | — | CN | disclosed |