Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28319304 | 0.90 | ADRB2 (0.59) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL28320403 | 0.87 | ADRB2 (0.56) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL28319294 | 0.87 | ADRB2 (0.60) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL28872992 | 0.85 | ADRB2 (0.53) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL28320407 | 0.83 | ADRB2 (0.56) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL28319303 | 0.82 | ADRB2 (0.56) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL28876483 | 0.82 | ADRB2 (0.60) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL2426880 | 0.77 | ADRB1 (0.58) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL15206786 | 0.77 | ADRB1 (0.58) | ADRB2ADRB1CYP2D6NFKB1HIF1A | |
| SCHEMBL28872989 | 0.77 | ADRB1 (0.58) | ADRB2ADRB1CYP2D6NFKB1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110143886-B | Process for the preparation of beta-arylaminoalkols such as tulobuterol, chlorpropaline, isoadrenaline dichloride and sotalol | 北京化工大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-110143886-A | The method of the preparation such as beta-aromatic alkamine drug of tulobuterol, Clorprenaline, isoproterenol and Sotalol | 北京化工大学 | 2019-08-20 | — | — | CN | disclosed |