Quinolinic Acid

Quinolinic Acid

SCHEMBL28320479

O=C(O)c1cccnc1C(=O)O.c1cc[nH]c1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.79
ALDH1A1 P00352 5/20 0.79
MAPT P10636 2/20 0.79
ALOX15 P16050 2/20 0.79
CYP3A4 P08684 1/20 0.79
TSHR P16473 1/20 0.79
BLM P54132 1/20 0.79
AGER Q15109 1/20 0.79
NPSR1 Q6W5P4 1/20 0.79
L3MBTL1 Q9Y468 1/20 0.79
TDP1 Q9NUW8 1/20 0.53
NAPRT Q6XQN6 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
CYP1A2 P05177 1/20 0.50
LMNA P02545 1/20 0.50
KMT2A Q03164 1/20 0.48
GAA P10253 2/20 0.47
ASPH Q12797 3/20 0.45
KDM8 Q8N371 3/20 0.45
CA1 P00915 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinolinic Acid SCHEMBL27676801 0.89 KDM4E (1.00) KDM4EALDH1A1MAPTALOX15CYP3A4
Quinolinic Acid SCHEMBL343618 0.89 KDM4E (1.00) KDM4EALDH1A1MAPTALOX15CYP3A4
Quinolinic Acid SCHEMBL69230 0.89 KDM4E (1.00) KDM4EALDH1A1MAPTALOX15CYP3A4
Quinolinic Acid SCHEMBL29356188 0.89 KDM4E (1.00) KDM4EALDH1A1MAPTALOX15CYP3A4
Quinolinic Acid SCHEMBL890367 0.87 KDM4E (0.96) KDM4EALDH1A1MAPTALOX15CYP3A4
Quinolinic Acid SCHEMBL5361020 0.87 KDM4E (0.96) KDM4EALDH1A1MAPTALOX15CYP3A4
Quinolinic Acid SCHEMBL3744925 0.87 KDM4E (0.96) KDM4EALDH1A1MAPTALOX15CYP3A4
Quinolinic Acid SCHEMBL21326209 0.87 KDM4E (0.96) KDM4EALDH1A1MAPTALOX15CYP3A4
Quinolinic Acid SCHEMBL5674125 0.87 KDM4E (0.96) KDM4EALDH1A1MAPTALOX15CYP3A4
Quinolinic Acid SCHEMBL7734169 0.87 KDM4E (0.96) KDM4EALDH1A1MAPTALOX15CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110216016-A Inhibitor for floatation separation of galena and active copper minerals 西北矿冶研究院 2019-09-10 CN disclosed