Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 8/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | BAD | Q92934 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28320551 | 0.85 | NFE2L2 (0.50) | NFE2L2PTGS1BCL2L1BAD | |
| SCHEMBL28321701 | 0.81 | NFE2L2 (0.43) | NFE2L2PTGS1PTGS2HTR2AHTR2C | |
| SCHEMBL28321737 | 0.78 | IDO1 (0.59) | NFE2L2IDO1 | |
| SCHEMBL13896466 | 0.76 | IDO1 (0.50) | IDO1 | |
| SCHEMBL29899236 | 0.76 | IDO1 (0.50) | IDO1 | |
| SCHEMBL28876780 | 0.76 | NFE2L2 (0.58) | NFE2L2PTGS1PTGS2HTR2AHTR2C | |
| SCHEMBL28321713 | 0.75 | NFE2L2 (0.48) | NFE2L2IDO1 | |
| SCHEMBL20995879 | 0.74 | NFE2L2 (1.00) | NFE2L2PTGS1PTGS2HTR2AHTR2C | |
| SCHEMBL20995875 | 0.74 | NFE2L2 (1.00) | NFE2L2PTGS1PTGS2HTR2AHTR2C | |
| SCHEMBL28320828 | 0.74 | NFE2L2 (0.43) | NFE2L2PTGS1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408325-B | cyanotriazole compounds | 大塚制药株式会社 | 2019-10-22 | — | — | CN | disclosed |