Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 9/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | BAD | Q92934 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28320659 | 0.85 | NFE2L2 (0.57) | NFE2L2PTGS1BCL2L1BAD | |
| SCHEMBL28320828 | 0.85 | NFE2L2 (0.43) | NFE2L2PTGS1HDAC1HPGD | |
| SCHEMBL28321799 | 0.82 | IDO1 (0.36) | HPGD | |
| SCHEMBL28321698 | 0.81 | NFE2L2 (0.44) | NFE2L2PTGS1APP | |
| SCHEMBL28321713 | 0.81 | NFE2L2 (0.48) | NFE2L2 | |
| SCHEMBL28321731 | 0.80 | NFE2L2 (0.40) | NFE2L2PTGS1 | |
| SCHEMBL29899236 | 0.78 | IDO1 (0.50) | RELA | |
| SCHEMBL13896466 | 0.78 | IDO1 (0.50) | RELA | |
| (Z)-1,2-Diphenylethene SCHEMBL29269291 | 0.78 | MAPK1 (0.44) | NFE2L2HPGD | |
| SCHEMBL4564602 | 0.77 | CDK8 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408325-B | cyanotriazole compounds | 大塚制药株式会社 | 2019-10-22 | — | — | CN | disclosed |