Sugi Predict

Sugi Predict / Compounds / SCHEMBL283216

SCHEMBL283216

SCHEMBL283216

C(=C1c2ccccc2-c2ccccc21)c1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP19A1 P11511 2/20 0.67
▸ CYP11B2 P19099 2/20 0.67
▸ TUBB4A P04350 1/20 0.47
▸ TUBB P07437 1/20 0.47
▸ TUBA3C P0DPH7 1/20 0.47
▸ AR P10275 1/20 0.47
▸ TUBA1B P68363 1/20 0.47
▸ TUBA4A P68366 1/20 0.47
▸ TUBB4B P68371 1/20 0.47
▸ TUBB3 Q13509 1/20 0.47
▸ TUBB2A Q13885 1/20 0.47
▸ TUBB8 Q3ZCM7 1/20 0.47
▸ TUBA3E Q6PEY2 1/20 0.47
▸ TUBA1A Q71U36 1/20 0.47
▸ TUBA1C Q9BQE3 1/20 0.47
▸ TUBB6 Q9BUF5 1/20 0.47
▸ TUBB2B Q9BVA1 1/20 0.47
▸ TUBB1 Q9H4B7 1/20 0.47
▸ HPGD P15428 4/20 0.45
▸ KDM4E B2RXH2 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4541307 0.97 CYP19A1 (0.62) CYP19A1CYP11B2TUBB4ATUBBTUBA3C
SCHEMBL4726286 0.85 TUBB4A (0.65) CYP19A1CYP11B2TUBB4ATUBBTUBA3C
SCHEMBL1225662 0.85 CYP19A1 (0.57) CYP19A1CYP11B2ALDH1A1L3MBTL1LMNA
SCHEMBL867959 0.83 CYP19A1 (0.60) CYP19A1CYP11B2TUBB4ATUBBTUBA3C
SCHEMBL8778480 0.82 TUBB4A (0.52) CYP19A1CYP11B2TUBB4ATUBBTUBA3C
SCHEMBL8778476 0.82 TUBB4A (0.52) CYP19A1CYP11B2TUBB4ATUBBTUBA3C
SCHEMBL25400816 0.82 HPGD (0.48) CYP19A1CYP11B2HPGDKDM4EALDH1A1
SCHEMBL9177130 0.82 CYP19A1 (0.48) CYP19A1CYP11B2TUBB4ATUBBTUBA3C
SCHEMBL9177137 0.82 CYP19A1 (0.48) CYP19A1CYP11B2TUBB4ATUBBTUBA3C
SCHEMBL19784873 0.80 CYP19A1 (0.57) CYP19A1CYP11B2TUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113717018-A Preparation method of 9-benzylmethylfluorene compound 温州大学 2021-11-30 — — CN claimed
CN-113717018-A Preparation method of 9-benzylmethylfluorene compound 温州大学 2021-11-30 — — CN disclosed
CN-113717018-A Preparation method of 9-benzylmethylfluorene compound 温州大学 2021-11-30 — — CN disclosed
CN-113480394-A Green synthesis method of alkylene fluorene 温州大学 2021-10-08 — — CN disclosed
US-9935271-B2 Organic electroluminescent device based on neutral free-radical electroluminescent material JILIN UNIVERSTIY (CN) 2018-04-03 — — US disclosed
US-9935271-B2 Organic electroluminescent device based on neutral free-radical electroluminescent material JILIN UNIVERSTIY (CN) 2018-04-03 — — US disclosed
EP-2265619-B1 [1]BENZOTHIENO[3,2-B][1]BENZOTHIOPHENE COMPOUND AND METHOD FOR PRODUCING THE SAME, AND ORGANIC ELECTRONIC DEVICE USING THE SAME RICOH CO LTD (JP) 2016-06-22 — — EP disclosed
US-20160099415-A1 ORGANIC ELECTROLUMINESCENT DEVICE BASED ON NEUTRAL FREE-RADICAL ELECTROLUMINESCENT MATERIAL JILIN UNIVERSITY (CN) 2016-04-07 — — US disclosed
US-9133211-B2 Dithienobenzodithiophene semiconductive material and electronic device using the same RICOH COMPANY, LTD. (JP) 2015-09-15 — — US disclosed
EP-2428527-B1 Carbazole polymer and method of manufacturing same RICOH CO LTD (JP) 2015-08-05 — — EP disclosed
US-20060247413-A1 pi-Conjugated polymer and manufacturing method thereof RICOH COMPANY, LTD. (JP) 2006-11-02 — — US disclosed
US-6593450-B2 Aromatic resins; electronics; films DOW GLOBAL TECHNOLOGIES INC. 2003-07-15 — — US disclosed
US-20010053842-A1 2,7-aryl-9-substituted fluorenes and 9-substituted fluorene oligomers and polymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-12-20 — — US disclosed
US-6255447-B1 OLIGOMERS OR POLYMERS WHICH DEMONSTRATE FLUORESCENCE, HIGH GLASS TRANSITION TEMPERATURES OR LIQUID-CRYSTALLINE PROPERTIES; FACILITATE PREPARATION OF FILMS HAVING HIGH HEAT RESISTANCE AND SOLVENT RESISTANCE THE DOW CHEMICAL COMPANY 2001-07-03 — — US disclosed
US-5962631-A 2, 7-aryl-9-substituted fluorenes and 9-substituted fluorene oligomers and polymers THE DOW CHEMICAL COMPANY (US) 1999-10-05 — — US disclosed
US-5708130-A 2,7-aryl-9-substituted fluorenes and 9-substituted fluorene oligomers and polymers THE DOW CHEMICAL COMPANY (US) 1998-01-13 — — US disclosed
EP-0149914-B1 OVERCOATED ELECTROPHOTOGRAPHIC IMAGING MEMBER XEROX CORPORATION (US) 1988-08-10 — — EP disclosed
US-4127475-A MULTISTAGE LIQUID CHROMATOGRAPHIC FRACTIONATION ELECTRIC POWER RESEARCH INSTITUTE, INC. (US) 1978-11-28 — — US disclosed
US-3966624-A LUBRICANTS SUN OIL COMPANY OF PENNSYLVANIA (US) 1976-06-29 — — US disclosed
US-3869496-A 2,7-BIS-BASIC ESTERS AND ETHERS OF 9-BENZYLIDENEFLUORENCE RICHARDSON MERRELL INC 1975-03-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160099415-A1 ORGANIC ELECTROLUMINESCENT DEVICE BASED ON NEUTRAL FREE-RADICAL ELECTROLUMINESCENT MATERIAL MT-ND4L, FARS2, GPX4 CYP19A1 3956/4885CYP11B2 957/4885TUBB4A 2019/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.