Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | P4HB | P07237 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28320622 | 0.88 | NFE2L2 (0.40) | NFE2L2TRPV1MAOBFBP1CHRNB2 | |
| SCHEMBL28321713 | 0.87 | NFE2L2 (0.48) | NFE2L2MAOBFBP1CHRNB2CHRNB4 | |
| SCHEMBL28321731 | 0.81 | NFE2L2 (0.40) | NFE2L2MAOBFBP1CHRNB2CHRNB4 | |
| SCHEMBL28320828 | 0.78 | NFE2L2 (0.43) | NFE2L2TRPV1MAOBCHRNB2CHRNB4 | |
| SCHEMBL5612780 | 0.77 | IDO1 (0.54) | MAOBIDO1MEN1KMT2A | |
| SCHEMBL17969165 | 0.75 | NFE2L2 (0.38) | NFE2L2TRPV1MAOBFBP1CHRNB2 | |
| SCHEMBL16399067 | 0.75 | NFE2L2 (0.38) | NFE2L2TRPV1MAOBFBP1CHRNB2 | |
| SCHEMBL21776857 | 0.73 | NOTUM (0.53) | — | |
| SCHEMBL28320535 | 0.73 | NFE2L2 (0.41) | NFE2L2MAOBFBP1CHRNB2CHRNB4 | |
| SCHEMBL16403019 | 0.72 | MAOB (0.55) | NFE2L2MAOBFBP1CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408325-B | cyanotriazole compounds | 大塚制药株式会社 | 2019-10-22 | — | — | CN | disclosed |