Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28321713 | 0.93 | NFE2L2 (0.48) | NFE2L2MAOBFBP1IDO1KDM4E | |
| SCHEMBL28320828 | 0.90 | NFE2L2 (0.43) | NFE2L2MAOBIDO1KDM4EPTGS1 | |
| SCHEMBL28321689 | 0.81 | NFE2L2 (0.41) | NFE2L2MAOBFBP1IDO1MAPT | |
| SCHEMBL5612780 | 0.80 | IDO1 (0.54) | MAOBIDO1KDM4EMEN1KMT2A | |
| SCHEMBL28320622 | 0.80 | NFE2L2 (0.40) | NFE2L2MAOBFBP1IDO1MAPT | |
| SCHEMBL28320551 | 0.80 | NFE2L2 (0.50) | NFE2L2PTGS1 | |
| SCHEMBL31144931 | 0.76 | IKBKB (0.37) | MAOBIDO1 | |
| SCHEMBL28321701 | 0.76 | NFE2L2 (0.43) | NFE2L2PTGS1 | |
| SCHEMBL28320659 | 0.74 | NFE2L2 (0.57) | NFE2L2IDO1PTGS1 | |
| SCHEMBL4564602 | 0.74 | CDK8 (0.44) | MAOBMAPTDYRK1ADYRK2DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408325-B | cyanotriazole compounds | 大塚制药株式会社 | 2019-10-22 | — | — | CN | disclosed |