Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 10/20 | 0.66 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.49 |
| ▸ | METAP2 | P50579 | 6/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28320524 | 0.91 | IDO1 (0.76) | IDO1MRGPRX4NOTUMMETAP2KEAP1 | |
| SCHEMBL28320616 | 0.85 | IDO1 (0.63) | IDO1NOTUMMETAP2KEAP1NFE2L2 | |
| SCHEMBL28321674 | 0.79 | IDO1 (0.66) | IDO1METAP2KEAP1 | |
| SCHEMBL28320828 | 0.76 | NFE2L2 (0.43) | IDO1NFE2L2NQO2 | |
| SCHEMBL28321726 | 0.75 | NFE2L2 (0.44) | NFE2L2NQO2 | |
| SCHEMBL28321737 | 0.74 | IDO1 (0.59) | IDO1METAP2KEAP1NFE2L2 | |
| SCHEMBL30567505 | 0.73 | IDO1 (0.56) | IDO1MRGPRX4NOTUMMETAP2KEAP1 | |
| SCHEMBL16399518 | 0.73 | ERBB2 (0.49) | NFE2L2NQO2 | |
| SCHEMBL16399521 | 0.73 | ERBB2 (0.49) | NFE2L2NQO2 | |
| SCHEMBL13790316 | 0.68 | NFE2L2 (0.82) | NFE2L2NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408325-B | cyanotriazole compounds | 大塚制药株式会社 | 2019-10-22 | — | — | CN | disclosed |