Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28321746 | 0.90 | NFE2L2 (0.49) | NFE2L2SCN2A | |
| SCHEMBL28321673 | 0.85 | NFE2L2 (0.51) | NFE2L2PTGS1HDAC1 | |
| SCHEMBL5020244 | 0.81 | SCN2A (0.56) | SCN2A | |
| SCHEMBL28321767 | 0.78 | IDO1 (0.40) | — | |
| SCHEMBL5020247 | 0.77 | SCN2A (0.46) | SCN2ATRPV1 | |
| SCHEMBL28321725 | 0.75 | IDO1 (0.66) | NFE2L2NQO2 | |
| SCHEMBL28320828 | 0.75 | NFE2L2 (0.43) | NFE2L2NQO2AHRPTGS1HDAC1 | |
| SCHEMBL28876780 | 0.74 | NFE2L2 (0.58) | NFE2L2PTGS1 | |
| SCHEMBL16398774 | 0.73 | NFE2L2 (0.39) | NFE2L2NQO2AHRPTGS1HDAC1 | |
| SCHEMBL16399319 | 0.73 | NFE2L2 (0.39) | NFE2L2NQO2AHRPTGS1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408325-B | cyanotriazole compounds | 大塚制药株式会社 | 2019-10-22 | — | — | CN | disclosed |