Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | P4HB | P07237 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28321726 | 0.90 | NFE2L2 (0.44) | NFE2L2SCN2A | |
| SCHEMBL5020244 | 0.88 | SCN2A (0.56) | SCN2AIDO1NPY5RPIM1 | |
| SCHEMBL28321673 | 0.80 | NFE2L2 (0.51) | NFE2L2MAOB | |
| SCHEMBL28876780 | 0.75 | NFE2L2 (0.58) | NFE2L2 | |
| SCHEMBL28321713 | 0.74 | NFE2L2 (0.48) | NFE2L2FBP1DYRK1ADYRK2DYRK1B | |
| SCHEMBL28321767 | 0.74 | IDO1 (0.40) | FBP1IDO1NPY5RLMNAMAPT | |
| SCHEMBL28320524 | 0.74 | IDO1 (0.76) | NFE2L2FBP1IDO1 | |
| SCHEMBL13790316 | 0.73 | NFE2L2 (0.82) | NFE2L2FBP1P4HBMAOBMEN1 | |
| SCHEMBL16399454 | 0.72 | NFE2L2 (0.43) | NFE2L2FBP1DYRK1ADYRK2DYRK1B | |
| SCHEMBL16403185 | 0.72 | NFE2L2 (0.43) | NFE2L2FBP1DYRK1ADYRK2DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408325-B | cyanotriazole compounds | 大塚制药株式会社 | 2019-10-22 | — | — | CN | disclosed |