Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 4/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | PHF8 | Q9UPP1 | 6/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28320545 | 0.85 | IDO1 (0.58) | NOTUMIDO1SRD5A2MRGPRX4PHF8 | |
| SCHEMBL28321766 | 0.82 | SRD5A2 (0.43) | SRD5A2MRGPRX4SRD5A1NR1H2QPCT | |
| SCHEMBL16398985 | 0.80 | SRD5A2 (0.39) | SRD5A2PHF8SRD5A1MPONR1H2 | |
| SCHEMBL28321728 | 0.79 | SRD5A2 (0.42) | SRD5A2SRD5A1NR1H2QPCT | |
| SCHEMBL16399554 | 0.76 | SRD5A2 (0.39) | SRD5A2SRD5A1NR1H2QPCT | |
| SCHEMBL18002464 | 0.74 | SRD5A2 (0.50) | SRD5A2SRD5A1NR1H2 | |
| SCHEMBL16399733 | 0.74 | SRD5A2 (0.39) | SRD5A2SRD5A1NR1H2QPCT | |
| SCHEMBL28321819 | 0.72 | SRD5A2 (0.45) | IDO1SRD5A2MRGPRX4SRD5A1MPO | |
| SCHEMBL18004446 | 0.69 | ESRRA (0.35) | SRD5A2SRD5A1 | |
| SCHEMBL28321745 | 0.68 | NOTUM (0.59) | NOTUMIDO1MRGPRX4PHF8NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408325-B | cyanotriazole compounds | 大塚制药株式会社 | 2019-10-22 | — | — | CN | disclosed |