Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | PI4KA | P42356 | 2/20 | 0.57 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.57 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.57 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | XDH | P47989 | 1/20 | 0.57 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.57 |
| ▸ | CDC7 | O00311 | 7/20 | 0.54 |
| ▸ | DBF4 | Q9UBU7 | 7/20 | 0.54 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2888994 | 0.83 | G6PD (1.00) | G6PDHSD17B10TP53LMNAPI4KA | |
| SCHEMBL31606731 | 0.83 | G6PD (1.00) | G6PDHSD17B10TP53LMNAPI4KA | |
| SCHEMBL30132912 | 0.80 | HSD17B10 (1.00) | G6PDHSD17B10TP53LMNAPI4KA | |
| SCHEMBL1884553 | 0.80 | G6PD (0.71) | G6PDHSD17B10TP53LMNAPI4KA | |
| SCHEMBL240980 | 0.80 | HSD17B10 (1.00) | G6PDHSD17B10TP53LMNAPI4KA | |
| SCHEMBL10840236 | 0.78 | HSD17B10 (0.96) | G6PDHSD17B10TP53LMNAPI4KA | |
| SCHEMBL10840233 | 0.78 | HSD17B10 (0.96) | G6PDHSD17B10TP53LMNAPI4KA | |
| SCHEMBL2888366 | 0.77 | G6PD (0.67) | G6PDHSD17B10TP53LMNAPI4KA | |
| SCHEMBL14447502 | 0.76 | TP53 (0.66) | G6PDHSD17B10TP53LMNAPI4KA | |
| SCHEMBL2115555 | 0.76 | PAK1 (0.71) | G6PDHSD17B10TP53LMNACDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177781-A | Bruton's tyrosine kinase inhibitor | BIOCAD股份有限公司 | 2019-08-27 | — | — | CN | disclosed |