SCHEMBL2888366

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31606731	0.80	G6PD (1.00)	G6PDHSD17B10TP53CDC7DBF4
	SCHEMBL2888994	0.80	G6PD (1.00)	G6PDHSD17B10TP53CDC7DBF4
	SCHEMBL1884553	0.77	G6PD (0.71)	G6PDHSD17B10TP53CDC7DBF4
	SCHEMBL28322010	0.77	G6PD (0.71)	G6PDHSD17B10TP53CDC7DBF4
	SCHEMBL240980	0.77	HSD17B10 (1.00)	G6PDHSD17B10TP53CDC7DBF4
	SCHEMBL30132912	0.77	HSD17B10 (1.00)	G6PDHSD17B10TP53CDC7DBF4
	SCHEMBL2891519	0.76	MAP3K5 (0.64)	HSD17B10TP53HIF1ACYP1A2CYP3A4
	SCHEMBL10840233	0.76	HSD17B10 (0.96)	G6PDHSD17B10TP53CDC7DBF4
	SCHEMBL10840236	0.76	HSD17B10 (0.96)	G6PDHSD17B10TP53CDC7DBF4
	SCHEMBL1607122	0.73	PI4KA (0.52)	G6PDHSD17B10TP53CDC7DBF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.