Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2386652 | 0.71 | PKM (0.66) | POLBHTTCYP1A2ALDH1A1NPC1 | |
| SCHEMBL16833409 | 0.70 | MAPT (0.50) | POLBHTTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL18421518 | 0.69 | PKM (0.53) | POLBHTTCYP3A4RECQLALDH1A1 | |
| SCHEMBL4561817 | 0.69 | PKM (0.48) | POLBHTTCYP3A4RECQLALDH1A1 | |
| SCHEMBL3279266 | 0.69 | PKM (0.48) | POLBHTTCYP3A4RECQLALDH1A1 | |
| SCHEMBL22574808 | 0.69 | PKM (0.41) | POLBHTTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19762435 | 0.69 | PKM (0.41) | POLBHTTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL22574809 | 0.68 | POLB (0.43) | POLBHTTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL22574804 | 0.68 | MAPT (0.44) | POLBHTTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27848575 | 0.67 | SMN1; SMN2 (0.43) | POLBHTTCYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108084177-B | A kind of jamaicin 9- pyrazole derivatives and its preparation and application | 中南大学 | 2019-10-08 | — | — | CN | disclosed |
| CN-108084177-A | A kind of jamaicin 9- pyrazole derivatives and its preparation and application | 中南大学 | 2018-05-29 | — | — | CN | disclosed |