Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrazine SCHEMBL28281912 | 0.79 | PKM (0.49) | PKMPOLBHTTLMNANPC1 | |
| SCHEMBL2386652 | 0.77 | PKM (0.66) | PKMPOLBHTTLMNANPC1 | |
| SCHEMBL18421518 | 0.75 | PKM (0.53) | PKMPOLBHTTLMNANPC1 | |
| SCHEMBL3279266 | 0.75 | PKM (0.48) | PKMPOLBHTTLMNANPC1 | |
| SCHEMBL18354808 | 0.73 | NPC1 (0.56) | PKMPOLBHTTLMNANPC1 | |
| SCHEMBL8657291 | 0.71 | HTT (0.57) | POLBHTTLMNANPC1RAB9A | |
| SCHEMBL13791534 | 0.70 | PKM (0.52) | PKMPOLBHTTLMNANPC1 | |
| SCHEMBL19875281 | 0.69 | PKM (0.47) | PKMPOLBHTTLMNANPC1 | |
| SCHEMBL28322110 | 0.69 | POLB (0.47) | PKMPOLBHTTLMNANPC1 | |
| SCHEMBL2386649 | 0.69 | PKM (0.61) | PKMPOLBLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111235597-B | Synthesis method of nitroazole energetic compound | 南京理工大学 | 2020-10-30 | — | — | CN | disclosed |
| CN-111235597-A | Synthesis method of nitroazole energetic compound | 南京理工大学 | 2020-06-05 | — | — | CN | disclosed |
| US-20130059841-A1 | THERAPEUTIC COMPOSITIONS AND METHODS | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2013-03-07 | — | — | US | disclosed |
| US-8318741-B2 | Therapeutic compositions and methods | THE TEXAS A & M UNIVERSITY SYSTEM (US) | 2012-11-27 | — | — | US | disclosed |
| US-20120196868-A1 | THERAPEUTIC COMPOSITIONS AND METHODS | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2012-08-02 | — | — | US | disclosed |
| US-20120115959-A1 | Therapeutic Compositions And Methods | THE TEXAS A&M UNIVERSITY SYSTEM | 2012-05-10 | — | — | US | disclosed |
| US-20120071485-A1 | Therapeutic Compositions And Methods | THE TEXAS A&M UNIVERSITY SYSTEM | 2012-03-22 | — | — | US | disclosed |
| US-8088773-B2 | Therapeutic compositions and methods | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2012-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115959-A1 | Therapeutic Compositions And Methods | PDE6C, PDE6H, PDE6D | PKM 1733/4885POLB 3074/4885HTT 581/4885 |
| US-20120071485-A1 | Therapeutic Compositions And Methods | PDE6H, PDE6C, PDE6D | PKM 1971/4885POLB 3479/4885HTT 145/4885 |
| US-20120196868-A1 | THERAPEUTIC COMPOSITIONS AND METHODS | PDE6H, PDE6C, PDE6D | PKM 1971/4885POLB 3479/4885HTT 145/4885 |
| US-20130059841-A1 | THERAPEUTIC COMPOSITIONS AND METHODS | PDE6H, PDE6C, PDE6D | PKM 1971/4885POLB 3479/4885HTT 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.