SCHEMBL28323508

SCHEMBL28323508

CN1CN(C)c2ccccc21.F[B-](F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
GAA P10253 3/20 0.52
KDM4E B2RXH2 1/20 0.52
MAPT P10636 1/20 0.52
HPGD P15428 1/20 0.52
CES1 P23141 5/20 0.39
BCHE P06276 2/20 0.39
ALDH3A1 P30838 3/20 0.35
ALDH2 P05091 2/20 0.35
MAOA P21397 1/20 0.34
CDC25A P30304 1/20 0.34
TP53 P04637 1/20 0.33
ADRA2C P18825 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
PARK7 Q99497 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL178983 0.89 ALDH1A1 (0.61) ALDH1A1GAAKDM4EMAPTHPGD
SCHEMBL29444128 0.89 ALDH1A1 (0.61) ALDH1A1GAAKDM4EMAPTHPGD
Bromide SCHEMBL31722794 0.87 ALDH1A1 (0.58) ALDH1A1GAAKDM4EMAPTHPGD
Lithium SCHEMBL31260774 0.87 ALDH1A1 (0.58) ALDH1A1GAAKDM4EMAPTHPGD
Iodide SCHEMBL30935723 0.87 ALDH1A1 (0.58) ALDH1A1GAAKDM4EMAPTHPGD
Iodide SCHEMBL354263 0.87 ALDH1A1 (0.58) ALDH1A1GAAKDM4EMAPTHPGD
Bromide SCHEMBL9328396 0.87 ALDH1A1 (0.58) ALDH1A1GAAKDM4EMAPTHPGD
Hydrochloric Acid SCHEMBL5146630 0.87 ALDH1A1 (0.58) ALDH1A1GAAKDM4EMAPTHPGD
SCHEMBL28365588 0.78 ALDH1A1 (0.43) ALDH1A1GAAKDM4EMAPTHPGD
SCHEMBL15763560 0.77 ALDH1A1 (0.48) ALDH1A1GAAKDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110357770-B Method for preparing lactic acid through selective catalytic conversion of ethylene glycol 复旦大学 2021-10-26 CN disclosed
CN-110357770-A A kind of method that glycol selectivity catalyzed conversion prepares lactic acid 复旦大学 2019-10-22 CN disclosed