Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL31722794 | 1.00 | ALDH1A1 (0.58) | ALDH1A1GAAHPGDMAPTKDM4E | |
| SCHEMBL29444128 | 0.97 | ALDH1A1 (0.61) | ALDH1A1GAAHPGDMAPTKDM4E | |
| SCHEMBL178983 | 0.97 | ALDH1A1 (0.61) | ALDH1A1GAAHPGDMAPTKDM4E | |
| Lithium SCHEMBL31260774 | 0.94 | ALDH1A1 (0.58) | ALDH1A1GAAHPGDMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL5146630 | 0.94 | ALDH1A1 (0.58) | ALDH1A1GAAHPGDMAPTKDM4E | |
| Iodide SCHEMBL354263 | 0.94 | ALDH1A1 (0.58) | ALDH1A1GAAHPGDMAPTKDM4E | |
| Iodide SCHEMBL30935723 | 0.94 | ALDH1A1 (0.58) | ALDH1A1GAAHPGDMAPTKDM4E | |
| SCHEMBL28323508 | 0.87 | ALDH1A1 (0.52) | ALDH1A1GAAHPGDMAPTKDM4E | |
| SCHEMBL15763560 | 0.83 | ALDH1A1 (0.48) | ALDH1A1GAAHPGDMAPTKDM4E | |
| Acetic Acid SCHEMBL29250276 | 0.83 | GAA (0.48) | ALDH1A1GAAHPGDMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398358-B1 | Aluminum electroplating method | MITSUBISHI PETROCHEMICAL CO (JP) | 1994-03-09 | — | — | EP | claimed |
| US-5041194-A | Using low melting mixture of aluminum halide and onium halide of nitrogen-containing compound | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1991-08-20 | — | — | US | claimed |
| JP-3061392-A | — | — | None | — | — | JP | disclosed |
| EP-0398358-B1 | Aluminum electroplating method | MITSUBISHI PETROCHEMICAL CO (JP) | 1994-03-09 | — | — | EP | disclosed |
| US-5041194-A | Using low melting mixture of aluminum halide and onium halide of nitrogen-containing compound | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1991-08-20 | — | — | US | disclosed |
| JP-H0361392-A | COMPOSITION HAVING LOW MELTING POINT AND ALUMINUM ELECTROPLATING METHOD USING THE SAME AS BATH | MITSUBISHI PETROCHEM CO LTD | 1991-03-18 | — | — | JP | disclosed |
| EP-0398358-A2 | Aluminum electroplating method | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1990-11-22 | — | — | EP | disclosed |