SCHEMBL28323802

SCHEMBL28323802

O=C(OOC(=O)c1ccccc1Cc1ccccc1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.57
F2 P00734 1/20 0.57
TSHR P16473 2/20 0.54
SCN1A P35498 1/20 0.50
SCN2A Q99250 1/20 0.50
SCN3A Q9NY46 1/20 0.50
KMT2A Q03164 4/20 0.48
MEN1 O00255 3/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
KDM4E B2RXH2 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
TDP1 Q9NUW8 2/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A3 Q01959 1/20 0.47
MAPT P10636 4/20 0.47
ALDH1A1 P00352 2/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2D6 P10635 2/20 0.47
CYP2C9 P11712 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11129391 0.93 TSHR (0.56) LMNATSHRSCN1ASCN2ASCN3A
SCHEMBL6566314 0.91 LMNA (0.54) LMNAF2TSHRSCN1ASCN2A
SCHEMBL6266933 0.83 TSHR (0.50) LMNATSHRSCN1ASCN2ASCN3A
SCHEMBL27717707 0.82 SCN1A (0.49) LMNATSHRSCN1ASCN2ASCN3A
SCHEMBL1930582 0.81 SCN1A (0.57) LMNATSHRSCN1ASCN2ASCN3A
SCHEMBL6272312 0.80 TSHR (0.62) TSHRTDP1MAPTALDH1A1CYP1A2
SCHEMBL7918499 0.80 SCN1A (0.48) LMNATSHRSCN1ASCN2ASCN3A
SCHEMBL3372645 0.79 TSHR (0.53) LMNATSHRSCN1ASCN2ASCN3A
SCHEMBL4285614 0.79 SCN1A (0.56) LMNATSHRSCN1ASCN2ASCN3A
SCHEMBL905244 0.79 ALDH1A1 (0.63) LMNATSHRSCN1ASCN2ASCN3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110144106-A A kind of resisting etiolation light guide plate and preparation method thereof 嘉创新材料(浙江)有限公司 2019-08-20 CN disclosed