Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
| ▸ | CCR8 | P51685 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29401687 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1AHRKDM4ELMNA | |
| SCHEMBL29424134 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1AHRKDM4ELMNA | |
| SCHEMBL84051 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1AHRKDM4ELMNA | |
| SCHEMBL5041519 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1AHRKDM4ELMNA | |
| Methane SCHEMBL8775730 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1AHRKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL18039122 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1AHRKDM4ELMNA | |
| SCHEMBL2435903 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1AHRKDM4ELMNA | |
| Bromide SCHEMBL22440321 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1AHRKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL30785438 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1AHRKDM4ELMNA | |
| SCHEMBL28480196 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1AHRKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110382478-A | 2,6- Disubstituted pyridine derivatives | 大日本住友制药株式会社 | 2019-10-25 | — | — | CN | disclosed |