Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
| ▸ | CCR8 | P51685 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31036835 | 0.88 | SMN1; SMN2 (0.54) | SMN1; SMN2L3MBTL1NOS3NOS1NOS2 | |
| SCHEMBL3756885 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1NOS3NOS1NOS2 | |
| Hydrazine SCHEMBL28365317 | 0.83 | L3MBTL1 (0.54) | SMN1; SMN2L3MBTL1NOS3NOS1NOS2 | |
| SCHEMBL864064 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1NOS3NOS1NOS2 | |
| SCHEMBL84051 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1NOS3NOS1NOS2 | |
| SCHEMBL29401687 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1NOS3NOS1NOS2 | |
| SCHEMBL5041519 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1NOS3NOS1NOS2 | |
| SCHEMBL29424134 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1NOS3NOS1NOS2 | |
| Bromide SCHEMBL22440321 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1NOS3NOS1NOS2 | |
| Methane SCHEMBL8775730 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8974771-B2 | Apparatus and method for aerosol delivery to the lungs or other locations of the body | Penn-Century, Inc. (US) | 2015-03-10 | — | — | US | disclosed |
| US-20110223116-A1 | APPARATUS AND METHOD FOR AEROSOL DELIVERY TO THE LUNGS OR OTHER LOCATIONS OF THE BODY | Penn-Century, Inc. (US) | 2011-09-15 | — | — | US | disclosed |