SCHEMBL2832398

SCHEMBL2832398

Cc1nc2c(Br)c3nsnc3c(Br)c2nc1C

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 1/20 0.34
LMNA P02545 2/20 0.31
PRNP P04156 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
NOD2 Q9HC29 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16702735 0.84 NQO2 (0.42) NQO2LMNAPRNPHPGDHTT
SCHEMBL26194074 0.78 MAPT (0.33) NQO2
SCHEMBL5655492 0.76 MEN1 (0.32)
SCHEMBL768983 0.74 MEN1 (0.31)
SCHEMBL23482399 0.70 MEN1 (0.32)
SCHEMBL14666867 0.70 MEN1 (0.32)
SCHEMBL17755560 0.70
SCHEMBL27896649 0.69 NQO2 (0.37) NQO2LMNAPRNPHPGDHTT
SCHEMBL24421891 0.69 LMNA (0.44) NQO2LMNAPRNPHPGDHTT
SCHEMBL19924692 0.69 NQO2 (0.37) NQO2LMNAPRNPHPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240327568-A1 OPEN-SHELL CONJUGATED POLYMER CONDUCTORS, COMPOSITES, AND COMPOSITIONS UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2024-10-03 US disclosed
US-12043698-B2 Open-shell conjugated polymer conductors, composites, and compositions UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2024-07-23 US disclosed
US-12043698-B2 Open-shell conjugated polymer conductors, composites, and compositions UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2024-07-23 US disclosed
US-12043698-B2 Open-shell conjugated polymer conductors, composites, and compositions UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2024-07-23 US disclosed
US-20240092965-A1 OPEN-SHELL CONJUGATED POLYMER CONDUCTORS, COMPOSITES, AND COMPOSITIONS UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2024-03-21 US disclosed
US-11773211-B2 Open-shell conjugated polymer conductors, composites, and compositions UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2023-10-03 US disclosed
US-11773211-B2 Open-shell conjugated polymer conductors, composites, and compositions UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2023-10-03 US disclosed
US-11773211-B2 Open-shell conjugated polymer conductors, composites, and compositions UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2023-10-03 US disclosed
CN-113563366-B Azacycloacene compound and preparation method thereof 阜阳欣奕华材料科技有限公司 2023-02-28 CN disclosed
US-20220332870-A1 Narrow Band Gap Conjugated Polymers Employing Cross-Conjugated Donors Useful In Electronic Devices THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2022-10-20 US disclosed
US-20180371157-A1 THIADIAZOLOPYRIDINE POLYMERS, THEIR SYNTHESIS AND THEIR USE MERCK PATENT GMBH (DE) 2018-12-27 US disclosed
EP-3390496-A1 THIADIAZOLOPYRIDINE POLYMERS, THEIR SYNTHESIS AND THEIR USE Merck Patent GmbH (DE) 2018-10-24 EP disclosed
US-20180142153-A1 THIADIAZOLOQUINOXALINE DERIVATIVES MERCK PATENT GMBH (DE) 2018-05-24 US disclosed
WO-2018039347-A2 NARROW BAND GAP CONJUGATED POLYMERS EMPLOYING CROSS-CONJUGATED DONORS USEFUL IN ELECTRONIC DEVICES AZOULAY JASON D (US) 2018-03-01 WO disclosed
WO-2017102058-A1 THIADIAZOLOPYRIDINE POLYMERS, THEIR SYNTHESIS AND THEIR USE MERCK PATENT GMBH (DE) 2017-06-22 WO disclosed
US-20130231456-A1 GREEN TO TRANSMISSIVE SOLUBLE ELECTROCHROMIC POLYMERS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2013-09-05 US disclosed
US-7842758-B2 Conjugated materials featuring proquinoidal units THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2010-11-30 US disclosed
US-20090221762-A1 NOVEL CONJUGATED MATERIALS FEATURING PROQUINOIDAL UNITS THE TRUSSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2009-09-03 US disclosed
WO-2007081991-A9 NOVEL CONJUGATED MATERIALS FEATURING PROQUINOIDAL UNITS UNIV PENNSYLVANIA (US) 2007-09-07 WO disclosed
WO-2007081991-A2 NOVEL CONJUGATED MATERIALS FEATURING PROQUINOIDAL UNITS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2007-07-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090221762-A1 NOVEL CONJUGATED MATERIALS FEATURING PROQUINOIDAL UNITS PML, ILK, PARG NQO2 1034/4885LMNA 43/4885PRNP 130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.