Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | AS3MT | Q9HBK9 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28326137 | 0.81 | MAOB (0.51) | MAOBSGMS2SQORIMPDH2AS3MT | |
| Hydrochloric Acid SCHEMBL28877629 | 0.80 | FEN1 (0.39) | MAOBFEN1SGMS2ALOX5APSQOR | |
| SCHEMBL28326121 | 0.78 | MAOB (0.51) | MAOBSGMS2SQORIMPDH2AS3MT | |
| Fluoride SCHEMBL28325117 | 0.74 | MAOB (0.56) | MAOBSGMS2SQORIMPDH2XDH | |
| SCHEMBL4452496 | 0.73 | MAOB (0.56) | MAOBSQORIMPDH2AS3MTNSD2 | |
| SCHEMBL6950623 | 0.71 | MAOB (0.54) | MAOBIMPDH2XDH | |
| SCHEMBL8727263 | 0.71 | MAOB (0.50) | MAOBIMPDH2AS3MTXDHFNTA | |
| SCHEMBL4309390 | 0.71 | MAOB (0.50) | MAOBIMPDH2XDHFNTAFNTB | |
| SCHEMBL6915950 | 0.71 | MAOB (0.53) | MAOBSQORIMPDH2XDH | |
| SCHEMBL769653 | 0.70 | XDH (0.57) | MAOBXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156698-A | The preparation method and purposes of 2- phenyl -1,6- dihydro-pyrimidin -5- formic acid derivates | 沈阳海诺威医药科技有限公司 | 2019-08-23 | — | — | CN | disclosed |